| Acronym | Definition |
|---|
| SPEAR | Social Policy Evaluation and Research (New Zealand) |
| SPEAR | Society for the Promotion of Education and Research (Belize) |
| SPEAR | Spontaneous Protection Enabling Accelerated Response (self defense system) |
| SPEAR | Stanford Positron Electron Accelerating Ring (particle physics accelerator) |
| SPEAR | Special Operations Forces Equipment Advanced Requirements |
| SPEAR | Security Protocol Engineering and Analysis Resource |
| SPEAR | Seismic Performance Assessment and Rehabilitation (EU research project) |
| SPEAR | Surface Profile Analysis Reflectometer |
| SPEAR | Speech Enhancement Assessment Resource |
| SPEAR | Selectable Precision Effects At Range |
| SPEAR | Selected Pollution Equipment Availability Register |
| SPEAR | Singapore Prisons Emergency and Action Response |
| SPEAR | Signal Processing Environment for Analysis and Reduction |
| SPEAR | Strategic Planning Enterprise Architecture and Requirements |
| SPEAR | SLQ-32 Program Evaluation And Review |
| SPEAR | Sustained Performance Excellence, Assessment and Review (trademark of Business Assessment Services; Pretoria, South Africa) |
| SPEAR | Signal Processing, Evaluation, Alerting & Reporting |
| SPEAR | Standardized Patriot Evaluation and Assessment Reporting (US Army Air Defense Artillery) |