SPEB
| Acronym | Definition |
|---|---|
| SPEB | Streptococcal Pyrogenic Exotoxin B (immunology) |
| SPEB | State Primary Education Board (Nigeria) |
| SPEB | Sidious-Palpatine Estrogen Brigade |
| SPEB | South Platte Enhancement Board (Denver, CO) |
| SPEB | Social and Political Environment of Business (course) |