| Acronym | Definition |
|---|
| SPEC | Specification |
| SPEC | Special (special operations) |
| SPEC | Standard Performance Evaluation Corporation |
| SPEC | Specialist |
| SPEC | Spectrum |
| SPEC | Specimen |
| SPEC | Spectrometry |
| SPEC | Standard Performance Evaluation Corp. (computer benchmarks; Gainesville, VA) |
| SPEC | Spelling Corrections |
| SPEC | Society Promoting Environmental Conservation |
| SPEC | Stakeholder Partnerships, Education and Communication (US IRS) |
| SPEC | Species of European Conservation Concern (ornithology) |
| SPEC | Systems Performance Evaluation Cooperative |
| SPEC | System Performance Evaluation Corporation |
| SPEC | Special Purposes Examination for Chiropractic |
| SPEC | South Pacific Bureau for Economic Cooperation (also seen as SPBEC) |
| SPEC | Stanford Project on Emerging Companies (Stanford Graduate School of Business; Palo Alto, CA) |
| SPEC | Students for the Preservation of Etiquette in Chess (TV show Fillmore!) |
| SPEC | Social, Political, Economic, Creative |
| SPEC | Singapore Previa Estima Club (car club) |
| SPEC | Space Environmental Compatibility |
| SPEC | Spa Pool Educational Council |
| SPEC | Support Programme for Employment Creation (EU) |
| SPEC | Support Problems Encountered Commonly |
| SPEC | Strategic Partnership Education and Communication |
| SPEC | Selection, Pre-qualification and Evaluation of Consultants |
| SPEC | Service des Programmes d'Etudes Canada (Canada) |
| SPEC | Sustaining Partnerships-Enhancing Collaboration (Wasington) |
| SPEC | Special Service, Reserve Pay Clerk (US Navy) |