| Acronym | Definition |
|---|
| SPDC | State Peace and Development Council (Myanmar) |
| SPDC | Shell Petroleum Development Company |
| SPDC | Self Protecting Digital Content |
| SPDC | Spontaneous Parametric Down Conversion |
| SPDC | Self-Protecting Digital Content |
| SPDC | Sokhna Port Development Company |
| SPDC | Security Post Dated Cheque (banking) |
| SPDC | Special Political and Decolonization Committee (UN) |
| SPDC | Spare Parts Distributing Center (US Navy) |
| SPDC | Surge Protective Devices Committee (IEEE) |
| SPDC | Swindon Practice Development Centre (UK) |
| SPDC | Sapang Palay Development Committee (Philippines) |