SPDI
| Acronym | Definition |
|---|---|
| SPDI | Sony Philips Digital Interface |
| SPDI | Secreted Protein Discovery Initiative |
| SPDI | Static Placement, Dynamic Issue |
| SPDI | Sustainable Policy Development Institute |
| SPDI | Students Promoting Dominican Ideals (Dominican University of California) |
| SPDI | Single Point Directional Interchange (roadways) |