| Acronym | Definition |
|---|
| SHC | Sears Holdings Corporation (Hoffman Estates, ILt) |
| SHC | Socket Head Cap (screws) |
| SHC | Self-Help Clearinghouse (Valley Cottage, NY) |
| SHC | Spring Hill College (Mobile, AL, USA) |
| SHC | Student Health Center (various schools) |
| SHC | Schreyer Honors College (Pennsylvania State University) |
| SHC | Sexual Health Centre (various locations) |
| SHC | Speech and Hearing Center (various locations) |
| SHC | Springfield Hospital Center (Maryland) |
| SHC | Storage Host Component |
| SHC | Sequence Header Code |
| SHC | Shape Curves |
| SHC | System Health Check |
| SHC | Spontaneous Human Combustion |
| SHC | Squalene-Hopene Cyclase (enzyme) |
| SHC | Solar Heating and Cooling |
| SHC | Sacred Heart College (Victoria, Australia) |
| SHC | Surrey History Centre (UK) |
| SHC | Societé Historique du Canada (French: Canadian Historical Association) |
| SHC | Self Help Center |
| SHC | Strategic Habitat Conservation (US FWS) |
| SHC | Stanford Hospital & Clinics |
| SHC | Sherbourne Health Centre (Ontario, Canada) |
| SHC | Specific Heat Capacity |
| SHC | Synthesized Hydrocarbon (Exxon Mobil lubricants) |
| SHC | School Health Council (various locations) |
| SHC | Saudi High Commission (Saudi Arabia) |
| SHC | Serious Health Condition |
| SHC | Scientific Humanitarian Committee (various organizations) |
| SHC | Indaselassie, Ethiopia (Airport Code) |
| SHC | Swedish Helsinki Committee (human rights organization; Stockholm, Sweden) |
| SHC | Scrapheap Challenge |
| SHC | Snowhawk Clan (gaming) |
| SHC | Stevens - Henager College |
| SHC | Senior Health Center |
| SHC | Space Heater Convective |
| SHC | Stock Holding Company |
| SHC | South Hadley Crew |
| SHC | Service Hydrographique Canadien (Canadian Hydrographic Service) |
| SHC | Submersible Hull Catamaran |
| SHC | Simone Home Care, Inc. (Columbus, OH) |
| SHC | Sacred Heart Cathedral Preparatory (San Francisco, CA; also seen as SHCH) |
| SHC | Special Handling Code |
| SHC | Senior Housing Council |
| SHC | Saginaw Housing Commission (Saginaw, Michigan) |
| SHC | Stop Human Cloning |
| SHC | Small Homes Council |
| SHC | Seat Heating Controller |
| SHC | Summer Hill Crew |
| SHC | Chief Ship's Serviceman (Naval Rating) |
| SHC | Surveillance Helicopter Company |
| SHC | Spiritual Health Coach |
| SHC | Symmetrized Hyperspherical Coordinate |
| SHC | Static Header Compression |
| SHC | Surface Hairline Crack |
| SHC | Sautron Hockey Club (France) |
| SHC | Superheat Controller |