| Acronym | Definition |
|---|
| TOM | Thomas |
| TOM | Tomorrow |
| TOM | Theory of Mind |
| TOM | Tokyo Otaku Mode (Tokyo, Japan) |
| TOM | Thomson Airways (various locations) |
| TOM | The Old Masters (record restoration) |
| TOM | Theory of Machines (course) |
| TOM | Tour of Missouri (road bicycle racing) |
| TOM | The Omega Man (movie) |
| TOM | Tune-O-Matic (guitar bridge) |
| TOM | Think Of Me |
| TOM | Territoires d'Outre Mer (French: Overseas Territory) |
| TOM | Technology & Operations Management (various schools) |
| TOM | Thunder over Michigan (air show) |
| TOM | The Outdoor Museum |
| TOM | Time On the Market |
| TOM | Text Object Model |
| TOM | Technical Operations Manager (BBC) |
| TOM | Top of the Mind (advertising) |
| TOM | Tome of Magic (gaming, Dungeons and Dragons) |
| TOM | Time Of Month |
| TOM | Task Order Manager |
| TOM | Target Operating Model |
| TOM | Terrestrial Organic Matter |
| TOM | Time of Menstruation |
| TOM | Atlantic Tomcod |
| TOM | Typed Object Model |
| TOM | Tigers of Memphis (University of Memphis mascot) |
| TOM | Task Order Management |
| TOM | Tricare Operations Manual (military healthcare) |
| TOM | Technical Operations Manual (various organizations) |
| TOM | Therapy Outcome Measure (efficacy indicator) |
| TOM | Task Ownership Matrix (clinical trials) |
| TOM | The Other Moderator |
| TOM | Take-Off Mass |
| TOM | Translocase of Outer Membrane |
| TOM | Target Object Map |
| TOM | Task Oriented Menu (Raptor Design Studio) |
| TOM | Task Oriented Management |
| TOM | Totally Obedient Moron (computer) |
| TOM | Transactional Object Model |
| TOM | Tunneling of Messages (GPRS) |
| TOM | Terminal Output Message |
| TOM | Total Outgassing Measurement |
| TOM | Technology Obsolescence Management |
| TOM | Telcom Operations Map (Telemanagement Forum) |
| TOM | Thru-Open-Match |