SOTU
| Acronym | Definition |
|---|---|
| SOTU | State of the Union (US presidential speech; also seen as SOTUS) |
| SOTU | Sounds of the Universe (Depeche Mode album) |
| SOTU | Special Operations Task Unit |
| SOTU | Slow on the Uptake (Internet slang) |
| SOTU | Secrets of the Universe (website; game) |
| SOTU | Symptom of the Universe (Black Sabbath song) |