| Acronym | Definition |
|---|
| S&D | Search & Destroy |
| S&D | Scratch & Dent |
| S&D | Service & Delivery |
| S&D | Stand and Deliver |
| S&D | Special and Differential (trade) |
| S&D | Supply & Demand |
| S&D | Special and Differential Treatment (various nations) |
| S&D | Sales and Distribution |
| S&D | Supply & Distribution |
| S&D | Soiled and Damaged (inventory) |
| S&D | Speech & Debate |
| S&D | Sewer & Drain (plumbing, pipe usage) |
| S&D | Skate and Destroy (game) |
| S&D | Selling & Distribution (commerce) |
| S&D | Studs & Duds (sports) |
| S&D | Suave and Debonair |
| S&D | Schiel & Denver (publishing company) |
| S&D | Single and Double Reduction Gears (US Navy) |
| S&D | Sickness and Diarrhea |
| S&D | Swipe & Deploy (marketing) |