| Acronym | Definition |
|---|
| SMCS | St. Michael's Choir School (Toronto, Ontario, Canada) |
| SMCS | Sky Mountain Charter School (Placerville, CA) |
| SMCS | School of Mathematics and Computer Science (various schools) |
| SMCS | St. Michael's Convent School (Pakistan) |
| SMCS | Shades Mountain Christian School (Hoover, AL) |
| SMCS | Science, Math, Computer Science |
| SMCS | St. Michael's College School (Toronto, Canada) |
| SMCS | State Mediation and Conciliation Service (California) |
| SMCS | Six Mile Cypress Slough (Florida) |
| SMCS | Sony Media Cloud Services (computing) |
| SMCS | Structural Mode Control System |
| SMCS | Standard Machinery Control System |
| SMCS | Survivable Mission Control Station |
| SMCS | Senior Chief Signalman (Naval Rating) |
| SMCS | Satellite Mission Control Subsystem |
| SMCS | Sales Marketing Communications System (GE) |
| SMCS | Service Management Center Support (Sprint) |
| SMCS | St. Mary's College, Shirva (India) |
| SMCS | Serial Copy Management Services |
| SMCS | Satellite Mobile Services Switching Center |
| SMCS | Self-Managing Computer System |