SMDE
| Acronym | Definition |
|---|---|
| SMDE | Static Mercury Drop Electrode |
| SMDE | Simulation Model Development Environment |
| SMDE | Self-Masked Dry Etching (nanotechnology) |
| SMDE | System-Managed Directory Entry (computing; IBM) |
| SMDE | Studies in Moral Development and Education (University of Illinois at Chicago; Chicago, IL) |
| SMDE | Stupid Melon Dumb Egg |