| Acronym | Definition |
|---|
| RGS | Royal Geographical Society |
| RGS | Rio Grande do Sul (Brazilian State) |
| RGS | Rio Grande Southern (railroad) |
| RGS | Royal Grammar School (UK) |
| RGS | Royal Grammar School (England) |
| RGS | Research and Graduate Studies (various schools) |
| RGS | Remote Graphics Software (high-performance remote desktop connection protocol) |
| RGS | Regulators of G Protein Signaling |
| RGS | Rockhampton Grammar School (Australia) |
| RGS | Reflection Grating Spectrometer |
| RGS | Raffles Girls' School (Singapore) |
| RGS | Remote Gaming Server (various companies) |
| RGS | Référentiel Général de Sécurité (French: General Repository Security) |
| RGS | Regional Geochemical Survey (Canada) |
| RGS | Religious of the Good Shepherd (religious order) |
| RGS | Remote Guardian System (defensive system) |
| RGS | Rieger Syndrome |
| RGS | Rigid Galvanized Steel |
| RGS | Random Good Stuff |
| RGS | Remote Ground Station |
| RGS | Requirements Generation System |
| RGS | Royal Gay Society (UK) |
| RGS | Regional Gliding School |
| RGS | Register Guidance System (QuadTech) |
| RGS | Red Green Show (TV comedy) |
| RGS | Relay Ground Stations |
| RGS | Remote Ground Sensor |
| RGS | Range Gate Stealer |
| RGS | Receiving Ground Station |
| RGS | Report Generating Software (IRS) |
| RGS | Rate Gyro System |
| RGS | Range Gate Stealing |
| RGS | Retained Gas Sampler |
| RGS | Russian Ground Segment |
| RGS | Reading Group Specialist code |
| RGS | Resource Generation System |
| RGS | Restructured General Support |
| RGS | Réseau Genre et Sexualité (French: Gender and Sexuality Network) |
| RGS | Rugeley Grammar School (UK) |