| Acronym | Definition |
|---|
| APCO | Architectural Products Company (Columbus, OH) |
| APCO | Alabama Power Company |
| APCO | Association of Public-Safety Communications Officials-International (Daytona Beach, FL and Alexandria, VA) |
| APCO | Air Pollution Control Officer |
| APCO | Appalachian Power Company (Columbus, OH) |
| APCO | Association of Public Safety Communication Officials |
| APCO | Andres Pirazzoli y Cia, Ltda (Chile) |
| APCO | Appomattox Court House National Historic Park (US National Park Service) |
| APCO | Asian Parasite Control Organization (est. 1974) |
| APCO | Air Pollution Coalition of Ontario (Canada) |
| APCO | Arterial Pressure Cardiac Output |
| APCO | Associated Police Communications Officers |
| APCO | Aperture Close Out |
| APCO | Administrative Professional Company Orientation |