SEFC
| Acronym | Definition |
|---|---|
| SEFC | Southeast False Creek (Vancouver, BC, Canada) |
| SEFC | Southeast Fisheries Center |
| SEFC | Southeast Federal Center (Washington, DC; US GSA) |
| SEFC | Sumitomo Electric Optical Fiber and Cable |
| SEFC | Sudden-Expansion Flow Chamber |
| SEFC | South End Fitness Center (Boston, MA) |
| SEFC | Search Engine Friendly Catalog (Nexternal software tool) |