| Acronym | Definition |
|---|
| WSC | Wayne State College |
| WSC | Westfield State College (Westfield, MA) |
| WSC | Winter Simulation Conference |
| WSC | Winter Symposium on Chemometrics |
| WSC | Water and Sewerage Corporation (Bahamas) |
| WSC | Westminster Shorter Catechism (theology) |
| WSC | Western State College (Colorado) |
| WSC | Western State Conference (est. 1950) |
| WSC | World Solar Challenge |
| WSC | World Scholar's Cup (Los Angeles, CA) |
| WSC | Weight-Shift Control (aviation) |
| WSC | Worcester State College (Worcester, MA, USA) |
| WSC | Westminster Seminary California (Escondido, CA) |
| WSC | Workstation Controller |
| WSC | Web Service Composition |
| WSC | Web Security Context |
| WSC | Workstation Standardization and Centralization |
| WSC | Web Service Client |
| WSC | Workstation Client |
| WSC | Windows Security Center |
| WSC | Web Server Cluster |
| WSC | Web Server Certificate |
| WSC | Windows Scriptlet |
| WSC | Web Safe Color |
| WSC | Wi-Fi Simple Configuration |
| WSC | Web Server Cache |
| WSC | Wingecarribee Shire Council (Australia) |
| WSC | Wonderswan Color (video game) |
| WSC | Windows Script Component |
| WSC | Wyong Shire Council (Australia) |
| WSC | Windows Security Center (Microsoft) |
| WSC | Williston State College (North Dakota) |
| WSC | World Scout Conference |
| WSC | Water Sustainability and Climate (US NSF) |
| WSC | World Sudoku Championship |
| WSC | Web Standards Curriculum (various organizations) |
| WSC | World Semiconductor Council |
| WSC | World Ski Championship |
| WSC | Washington Sports Clubs |
| WSC | Web Site Creation |
| WSC | World Series Cricket |
| WSC | Water Supply Commission (various locations) |
| WSC | World Sport Chicago (Chicago, IL) |
| WSC | Winston S. Churchill |
| WSC | Washington State College (now Washington State University) |
| WSC | Water Service Connection (utilities) |
| WSC | Water Survey of Canada |
| WSC | Web Self Care (online transactions) |
| WSC | White Sands Complex (New Mexico) |
| WSC | Web Service Component |
| WSC | Web Service Challenge |
| WSC | Water and Sanitation Committee (various organizations) |
| WSC | water-soluble carbohydrates |
| WSC | Weinheimer Senioren-Convent (German fraternity association) |
| WSC | Wall Street Concepts (New York, NY) |
| WSC | Women's Studies Center |
| WSC | Western Society of Criminology |
| WSC | Water-Steam Cycle (power plants) |
| WSC | Windows Server Catalog |
| WSC | Washington Service Corps (AmeriCorps) |
| WSC | Water Systems Council |
| WSC | World Space Congress |
| WSC | World Sindhi Congress (UK) |
| WSC | Work Station Crane (Gorbel) |
| WSC | Wycombe Sports Centre (UK) |
| WSC | Wednesday Slide Conference (Armed Forces Institute of Pathology) |
| WSC | Washington State Council |
| WSC | World Sushi Cup (food competition) |
| WSC | Water Standard Company (Monterey, CA) |
| WSC | West Side Connection (band) |
| WSC | Whitsunday Shire Council (Australia) |
| WSC | Washington State Collaborative (diabetes care) |
| WSC | World Service Center (FedEx) |
| WSC | White Spaces Coalition |
| WSC | Water Sustainability Committee (Canada) |
| WSC | Warfighting Support Center |
| WSC | Working Security Committee (US DoD) |
| WSC | World Series Contender (baseball) |
| WSC | Winter School on Chemometrics |
| WSC | Wi-Fi Simple Config |
| WSC | Weapon System Council |
| WSC | Work Station Controller |
| WSC | World Stroke Congress |
| WSC | Westlakes Scientific Consulting Ltd (UK) |
| WSC | Western States Center |
| WSC | Wheelock Student Center (University of Puget Sound) |
| WSC | Western Surety Company (Canada) |
| WSC | Washington Science Center (Rockville, MD) |
| WSC | Web Service Center |
| WSC | Waldorf Soccer Club (Maryland) |
| WSC | Warfighter Support Center (USAF-AC2ISRC) |
| WSC | Wandsworth Swimming Club (UK) |
| WSC | Waste Stream Characterization |
| WSC | World Standardization Conference |
| WSC | Warrenton Soaring Center (Virgina, aviation) |
| WSC | WIN Site Coordinator |
| WSC | Writeable Control Store |
| WSC | Warhead Safety Committee (UK) |
| WSC | Wulguru Stuart Cluden (Australia) |
| WSC | Warning Systems Controller |
| WSC | Warrior Support Center |
| WSC | Weapons Systems Code |
| WSC | Weapons System Coordinator |
| WSC | Weapons System Concept |
| WSC | Weighted Sum Code (algorithm) |
| WSC | Wide-Band Sinal Conditioner |
| WSC | Web Spam Challenge |
| WSC | Water Supply Cooperative |
| WSC | Westminster Security Company (various locations) |