| Acronym | Definition |
|---|
| S&S | Safe and Sound |
| S&S | Sugar and Spice (various locations) |
| S&S | Start & Stop |
| S&S | Sweet & Sour (sauce) |
| S&S | Simon & Schuster (Publisher) |
| S&S | Street and Strip (motorcycles) |
| S&S | Short and Sweet |
| S&S | Sticks and Stones (New Found Glory album) |
| S&S | Sense and Sensibility (novel) |
| S&S | Shoes and Socks |
| S&S | Stop and Shop |
| S&S | Signs & Symptoms |
| S&S | Supply & Service |
| S&S | Service and Support |
| S&S | Service and Subscription |
| S&S | Steering and Suspension (automotive technology) |
| S&S | Sea & Sun |
| S&S | Spicks & Specks (TV show; Australia) |
| S&S | Safeguards and Security |
| S&S | Sparkman and Stephens (yacht designer) |
| S&S | Security and Support |
| S&S | Supply and Support |
| S&S | Smith and Smith (formerly Smith and Stankos; motorcycle parts; Viola, WI) |
| S&S | Sword & Shield |
| S&S | Service and Systems |
| S&S | Sun and Shadows (online gaming community) |
| S&S | Sudden and Serious (illness) |
| S&S | Sayers and Scovill (funeral coach manufacturer) |
| S&S | Stars & Stripes Newspaper (European or Pacific Edition) |
| S&S | Savings and Slippage (USACE) |
| S&S | Status and Scheduling |
| S&S | Sword and Sorcery Studios (games) |
| S&S | Siganto & Stacey Pty Ltd |