| Acronym | Definition |
|---|
| TSAC | Telephone Services Advisory Committee |
| TSAC | Terminal Services Advanced Client |
| TSAC | Tennessee Student Assistance Corporation (Nashville, Tennessee) |
| TSAC | Terminal Services Advanced Client (Microsoft) |
| TSAC | TranSouth Athletic Conference (National Association of Intercollegiate Athletics) |
| TSAC | Technical and Scientific Advisory Committee |
| TSAC | Towing Safety Advisory Committee |
| TSAC | Tracking System Analytical Calibration (US NASA) |
| TSAC | The Science Advisory Committee |
| TSAC | The Saints Are Coming (Green Day song) |
| TSAC | Twentse Studenten Alpen Club (Dutch: Twente Student Alpine Club) |
| TSAC | Total Squared Asynchronous Correlation |
| TSAC | Tri-State Area Council (Boy Scouts) |
| TSAC | Telenex Switch Auto-Connect |
| TSAC | TACOM Security Assistance Center |
| TSAC | The Super Adventure Club (South Park TV show) |
| TSAC | Table Soccer Association of Canada (International Table Soccer Federation) |
| TSAC | The Springfield Anglican College (Australia) |
| TSAC | To Skin A Cat (indie film) |
| TSAC | Title, Subtitle, and Caption |
| TSAC | Tulane Study Abroad Committee |