| Acronym | Definition |
|---|
| TLR | Trailer |
| TLR | Toll Like Receptor (immunological research) |
| TLR | Twin Lens Reflex |
| TLR | Temple (University) Law Review |
| TLR | Team Losi Racing (est. 1980) |
| TLR | Tailor |
| TLR | Target Lesion Revascularization |
| TLR | Tiller |
| TLR | To Love Ru (Japanese manga series) |
| TLR | The Last Resort (gaming clan) |
| TLR | Transmission Loading Relief |
| TLR | Texas Law Review |
| TLR | Templar (gaming guild) |
| TLR | Tonic Labyrinthine Reflex |
| TLR | Teaching and Learning Responsibilities (UK educational initiative and job role) |
| TLR | Time Lapse Recorder |
| TLR | Tilburg Law Review (Tilburg University; Tilburg, Netherlands) |
| TLR | Total Loss Replacement |
| TLR | The Last Resistance (gaming clan) |
| TLR | The Last Royals (band) |
| TLR | Thomson Legal & Regulatory Ltd. (Australia) |
| TLR | Triangulation-Listening-Ranging (sonar; US Navy) |
| TLR | Thanet Local Radio (UK) |
| TLR | Transportation Librarians Roundtable (US Department of Transportation) |
| TLR | target loss ratio |
| TLR | Top Level Requirement(s) |
| TLR | Transmission-Line Resonator |
| TLR | Two Lochs Radio (UK, Scotland) |
| TLR | The Lord Reigns |
| TLR | Technical Letter Report |
| TLR | Telecommunications Leasing Request |
| TLR | Termination Liability Reserve |
| TLR | Transport Layer Retry |
| TLR | Tennis Live Radio |
| TLR | Traceability Link Recovery |
| TLR | Team Lost Rebels |