| Acronym | Definition |
|---|
| UPN | Union Pacific North (transportation) |
| UPN | User Principal Name (Microsoft Windows 2000) |
| UPN | Universidad Pedagógica Nacional (Spanish: National Pedagogical University; Mexico) |
| UPN | United Paramount Network |
| UPN | Unión del Pueblo Navarro (Navarrese People Union) |
| UPN | Universal Product Number |
| UPN | User Principal Name |
| UPN | Uniform Public Network |
| UPN | Unique Program Number |
| UPN | Umgekehrte Polnische Notation (German: Reversed Polish Notation) |
| UPN | Universal Product Number (product number for medical & surgical products; HIBCC) |
| UPN | Unique Pupil Number (UK student ID system) |
| UPN | Unión de Periodistas de Nicaragua (Spanish: Union of Journalists of Nicaragua) |
| UPN | Uruapan, Michoacan, Mexico (Airport Code) |
| UPN | United Pallet Network (UK) Ltd |
| UPN | Unique Project Number |
| UPN | Université Populaire Neuchâteloise (French: Popular University of Neuchâtel; Switzerland) |
| UPN | United Pallet Network (UK) |
| UPN | United Purple Nations (gaming) |
| UPN | Uniform Product Number |
| UPN | United Punk Nation |
| UPN | Union Patriótico Nacional (National Patriotic Union/Front; political party, Guatemala) |