| Acronym | Definition |
|---|
| UCSC | University of California, Santa Cruz (since 1965; Santa Cruz, California) |
| UCSC | University of South Carolina |
| UCSC | Universita Cattolica Sacro Cuore (Italian: Sacred Heart Catholic University) |
| UCSC | University of Colombo School of Computing (Colombo, Sri Lanka) |
| UCSC | University Code of Student Conduct (various schools) |
| UCSC | Upper Coomera State College (Upper Coomera, Queensland, Australia) |
| UCSC | University of Calgary Swim Club (Alberta, Canada) |
| UCSC | University Classified Staff Council (University of Texas Houston, Texas Medical Center) |
| UCSC | Universal Computer Source Code |