| Acronym | Definition |
|---|
| SPIR | Society for Pediatric Interventional Radiology |
| SPIR | System Problem/Improvement Report |
| SPIR | Sindicato de Profesionales de La Información de La Rioja (Spanish: Union of Information Professionals Rioja; Logrono, Spain) |
| SPIR | Spectroscopie Dans le Proche Infrarouge (French: Near Infrared Reflectance Spectroscopy) |
| SPIR | Symmetric Private Information Retrieval |
| SPIR | Samaritan's Purse International Relief (UK) |
| SPIR | Spare Parts List and Interchangeability Record |
| SPIR | Serviciul Politiei de Interventie Rapida (Romania) |
| SPIR | Shipboard Passive Infrared Sensor |
| SPIR | Spectral Presaturation by Inversion Recovery (MRI sequence) |
| SPIR | Short Perimeter Intrusion Radar |
| SPIR | Strategic Process Improvement and Reengineering (Office) |