| Acronym | Definition |
|---|
| STEM | Science, Technology, Engineering and Mathematics |
| STEM | Science, Technology, Engineering and Maths |
| STEM | Science, Technology, Engineering and Medicine |
| STEM | Six Through Eight Mathematics (education) |
| STEM | Standard Evaluation Material (American Society of Cinematographers, DCI digital imaging test movie) |
| STEM | Scanning Tunneling Electron Microscope |
| STEM | Scanning Tunneling Electron Microscopy |
| STEM | Soft Tissue Extensor Mechanism (orthopedics) |
| STEM | Secure Telephony Enabled Middlebox |
| STEM | Scanning Transmission Electron Microscope/Microscopy |
| STEM | Shaped Tube Electrolytic Machining |
| STEM | Studiecentrum Technologie Energie Milieu (Dutch: Technology, Energy and Environment Study) |
| STEM | Short-Term Evangelical Mission |
| STEM | Science and Technology Enterprise Management (Army Science and Technology) |
| STEM | Systems Telecommunications Engineering Manager |
| STEM | Space, Time, Energy, Mass |
| STEM | Strategic Traffic Enforcement Measures (Canada) |
| STEM | System Trainer and Exercise Module |
| STEM | Special Telemetry-Equipped Missile |