| Acronym | Definition |
|---|
| SSSS | Stand Still. Stay Silent (webcomic) |
| SSSS | Society for the Scientific Study of Sexuality |
| SSSS | Stainless Steel Sheet and Strip (coils) |
| SSSS | Scripless Securities Settlement System (stocks) |
| SSSS | Staphylococcal Scalded Skin Syndrome |
| SSSS | Sand Sports Super Show (trade show; Torrance, CA) |
| SSSS | Silent Sound Spread Spectrum (conspiracy theory) |
| SSSS | Society for Social Studies of Science |
| SSSS | Scandinavian Simvastatin Survival Study |
| SSSS | Standard Super Service Station (Longmont, CO) |
| SSSS | Students for Saving Social Security |
| SSSS | Selected for Special Security Screening (Transportation Security Administration code) |
| SSSS | Space Shuttle System Specification |
| SSSS | Small Satellites Systems and Services |
| SSSS | State Swim Swimming School (Australia) |
| SSSS | Software Suitability Supportability Statement |
| SSSS | Stop Being So Stupid |