| Acronym | Definition |
|---|
| SPOC | Single Point Of Contact |
| SPOC | Scrum Product Owner Certified |
| SPOC | Sex Professionals of Canada (est. 2001) |
| SPOC | Sydney Paralympic Organising Committee |
| SPOC | Shuttle Payload Operations Contractor (radio equipment) |
| SPOC | Single Point Of Control |
| SPOC | Space Operations Center |
| SPOC | Staffing Point of Contact |
| SPOC | Space Program Operations Contract (NASA) |
| SPOC | Stop Poisoning Our Community |
| SPOC | Search and Rescue Point of Contact |
| SPOC | Saturn Performance Owners Club |
| SPOC | Southampton Portable Occam Compiler |
| SPOC | Survey Plan Online Checker (computer application) |
| SPOC | State Police Officers Council (Iowa) |
| SPOC | Self-Propelled Outdoor Club |
| SPOC | Shuttle Payload of Opportunity Carrier (NASA) |
| SPOC | Single Parent Only Child (classification) |
| SPOC | Spontaneous Oscillatory Contraction (biophysics) |
| SPOC | Single Person of Contact |
| SPOC | Science Planning and Operations Center |
| SPOC | Single Point Orbit Calculator |
| SPOC | Steaming Pile of Crap |
| SPOC | Special Access Required (SAR) Programs Oversight Committee (USAF) |
| SPOC | Simple Pieces of Cloth (baby carrier) |
| SPOC | Supplemental Purchase Order Condition |
| SPOC | Sensorless Pump Off Controller (oilfield controller) |
| SPOC | Secondary Point of Contact |
| SPOC | Systems Programmer On Call |
| SPOC | Saint Peters Old Collegians (Australian football club) |