| Acronym | Definition |
|---|
| URI | Uniform Resource Identifier |
| URI | Universal Resource Identifier (web; less common) |
| URI | University of Rhode Island |
| URI | United Religions Initiative |
| URI | Upper Respiratory Infection |
| URI | Universidade Regional Integrada (Portuguese: Integrated Regional University; Brazil) |
| URI | United Rentals (various locations) |
| URI | Uniform Resource Indicator |
| URI | Universal Resource Indicator |
| URI | University Research Initiative |
| URI | User Resource Identifier |
| URI | Undergraduate Research Internship (various schools) |
| URI | Unified Resource Identifier |
| URI | Unidad de Reacción Inmediata (Spanish: Immediate Reaction Unit; Colombia) |
| URI | University Reactor Instrumentation |
| URI | Unidad Regional Independiente |
| URI | User Premises Equipment Regulatory Issues |
| URI | Uniform Random Interleaver |
| URI | Unsatisfactory Rotational Index |