| Acronym | Definition |
|---|
| TOSC | Tales of the Sword Coast (role-playing game) |
| TOSC | Technical Outreach Services for Communities |
| TOSC | Test and Operations Support Contract (US NASA) |
| TOSC | Test Operations Control Center |
| TOSC | The Optical Sciences Company |
| TOSC | Thurston Olympians Swim Club (Lacey, WA) |
| TOSC | Technical Outreach Support Centers |
| TOSC | Time of OSCillation |
| TOSC | The Optical Science Corporation |
| TOSC | Technical and Operational Support Committee (European Patent Organisation) |
| TOSC | Tactical Operations Systems Corps |
| TOSC | The Ordinary Service Crew (band) |