| Acronym | Definition |
|---|
| TOSCA | Topology and Orchestration Specification for Cloud Applications (Organization for the Advancement of Structured Information Standards) |
| TOSCA | Total Occlusion Study of Canada (cardiology) |
| TOSCA | Test of Self-Conscious Affect |
| TOSCA | Toxic Substance Control Act (also abbreviated TSCA) |
| TOSCA | Topography Supported Customized Ablation (cornea mapping in eye surgery) |
| TOSCA | Topological Oscillation Search with Kinematical Analysis |
| TOSCA | Text and Office Systems Content Architecture |
| TOSCA | Total Oxyradical Scavenging Capacity Assay |