| Acronym | Definition |
|---|
| TPO | The Philadelphia Orchestra (Pennsylvania) |
| TPO | Tokyo Philharmonic Orchestra (Tokyo, Japan) |
| TPO | Tribal Police Officer (Alaska) |
| TPO | Thyroid Peroxidase |
| TPO | Thrombopoietin |
| TPO | Tree Preservation Order (UK) |
| TPO | Triple Pelvic Osteotomy (veterinary medicine) |
| TPO | Thermoplastic Olefin |
| TPO | Transportation Planning Organization |
| TPO | Total Power Output |
| TPO | Trade Promotion Organization (various locations) |
| TPO | Third Party Only (auto insurance) |
| TPO | Temporary Protection Order |
| TPO | Temporary Protective Order |
| TPO | Transmitter Power Output |
| TPO | Training and Placement Officer (various organizations; India) |
| TPO | Temperature-Programmed Oxidation |
| TPO | Tree Protection Order (UK) |
| TPO | Third Party Origination (lending) |
| TPO | Time, Place, and Occasion (appropriate clothing and behavior) |
| TPO | Trade Promotion Optimization |
| TPO | Trainee Probation Officer (UK) |
| TPO | Treatment, Payment & Operations (HIPAA) |
| TPO | Technical Project Officer |
| TPO | Traveling Post Office |
| TPO | Transition Planning Office (various organizations) |
| TPO | Triple Peel on Opponent (croquet) |
| TPO | TRADOC Project Office (US Army) |
| TPO | Transition Program Office (various organizations) |
| TPO | Theatre Pipe Organ |
| TPO | Twisted Pair Only |
| TPO | Thermal Plastic Olefin |
| TPO | Terminal Performance Objective |
| TPO | Thermo-Plastic Polyolefin |
| TPO | Time-Proportional Output |
| TPO | Trade Paperback Original |
| TPO | Terahertz-wave Parametric Oscillator |
| TPO | Toshiba Philharmonic Orchestra |
| TPO | Transaction Processing Option |
| TPO | Teleport Program Office |
| TPO | Totally Pissed Off |
| TPO | Test Program Office |
| TPO | THAAD Project Office |
| TPO | Technical Publications Office |
| TPO | Time and Place of Occurrence |
| TPO | Test Program Outline |
| TPO | Technical Program Office |
| TPO | Technical Planning Objective |
| TPO | Total Product Offer |
| TPO | Telecommunications Program Objective |
| TPO | Test Process Optimization (software) |
| TPO | TACSIM Program Office |
| TPO | Trout Predator Online (website) |
| TPO | Terminal Program Office |
| TPO | Telecommunications Project Office |
| TPO | Tentative Program Objective |
| TPO | Tri-Service Medical Information System Program Office |
| TPO | Transports Pluviaud Organisation (French: Pluviaud Transportation Organization) |
| TPO | Track Production Officer (radar air surveillance) |
| TPO | Total Power Optimization |
| TPO | Topological Pre-Ordering |