| Acronym | Definition |
|---|
| SPSA | Single Plan for Student Achievement (California) |
| SPSA | Church of St, Paul and St. Andrew (New York) |
| SPSA | Southern Political Science Association (Statesboro, GA) |
| SPSA | Scottish Police Services Authority |
| SPSA | Southeastern Public Service Authority (Chesapeake, VA) |
| SPSA | Spotted Sandpiper (bird species Actitis macularia) |
| SPSA | South Pine Sports Association (Australia) |
| SPSA | Sunderland Pharmaceutical Students' Association (UK) |
| SPSA | Simultaneous Perturbation Stochastic Approximation |
| SPSA | St. Paul School of Aparri (Aparri, Philippines) |
| SPSA | School Psychology Student Association (various schools) |
| SPSA | St. Petersburg Sailing Association (Florida) |
| SPSA | Sevenoaks Primary School Association (UK) |
| SPSA | Spanish Peaks Staff Association (Spanish Peaks Scout Ranch) |
| SPSA | Safe Performance Self Assessment (various organizations) |
| SPSA | Sandy Pond Sportsmans Association (Sandy Creek, NY) |
| SPSA | South Plains Surgical Associates (Lubbock, TX) |
| SPSA | Special Projects School for Air (US Navy) |
| SPSA | Sienna Plantation Softball Association (Texas) |
| SPSA | Shy Past Students Association (India) |
| SPSA | Snorby Preconfigured Security Application (software) |
| SPSA | Southeastern Portable Sanitation Association (trade organization) |
| SPSA | Special Project Support Activity |
| SPSA | Southeast Pacific Swordfish Arrangement |
| SPSA | Suriname Practical Shooting Association |