| Acronym | Definition |
|---|
| TPSS | Tangipahoa Parish School System (Louisiana) |
| TPSS | Traction Power Substation (rail transportation electrification) |
| TPSS | Training and Performance Support Systems (educational technology) |
| TPSS | Takoma Park Silver Spring Co-op (food store; Maryland) |
| TPSS | The Playstation Show (podcast) |
| TPSS | Technology and Policy Student Society (Massachusetts Institute of Technology) |
| TPSS | Toxic Pot Shower Shock Syndrome |
| TPSS | Target Prioritization and Selection System |
| TPSS | Transition Plus Sustainability Solutions (Canada) |