| Acronym | Definition |
|---|
| TPU | Thermoplastic Polyurethane |
| TPU | Tomsk Polytechnic University (Russia) |
| TPU | Turbov Processing Unit (motherboards) |
| TPU | Thermoplastic Urethane |
| TPU | Turbo Pascal Unit |
| TPU | Taxe Professionnelle Unique (French: Single Professional Tax) |
| TPU | Troop Program Unit |
| TPU | Text Processing Utility (computer programming language; Digital Equipment Corporation) |
| TPU | Toroidal Power Unit (electrical power device) |
| TPU | Turbo Pascal Unit (file extension; Borland) |
| TPU | Transient Personnel Unit |
| TPU | Teenage Pregnancy Unit |
| TPU | Trailer Parts Unlimited (Huntsville, TX) |
| TPU | Time Processing Unit |
| TPU | Total Propagated Uncertainty |
| TPU | Tank and Pump Unit (fuel transport/disbursal system) |
| TPU | Teikyo Post University (Connecticut) |
| TPU | Transportation & Public Utilities |
| TPU | Tank Pump Unit |
| TPU | Transportation Plan Update |
| TPU | Torpedo Propulsion Upgrade |
| TPU | Timer Power Unit (explosive devices) |
| TPU | Tape Preparation Unit |
| TPU | Task Preparation Unit |
| TPU | Turret Processor Unit (Bradley Fighting Vehicle A3) |
| TPU | Target Power Uprate (nuclear) |
| TPU | Trained, Needs Practice, Untrained (US Army) |
| TPU | Transparency Profile Unit (color management scanning terminology) |
| TPU | Tenants Participation Unit |