SPSL
| Acronym | Definition |
|---|---|
| SPSL | South Puget Sound League (interscholastic sports league; Washington) |
| SPSL | Security Policy Specification Language |
| SPSL | Special-Purpose Simulation Language |
| SPSL | Shree Precoated Steels Ltd. (India) |
| SPSL | Short Period Superlattice |
| SPSL | Steam Pressed Scrim Lumber |
| SPSL | Slow Pitch Softball League (various locations) |