| Acronym | Definition |
|---|
| TBU | Tape Backup Unit |
| TBU | The Brotherhood of Unity (gaming clan) |
| TBU | To Be Updated |
| TBU | True But Useless |
| TBU | Tomas Bata University (Czech Republic, Zlin) |
| TBU | Thinkin' 'bout You |
| TBU | Tertiary Butyl (chemistry) |
| TBU | Transient Blocking Unit |
| TBU | Triune Biblical University (Kelso, WA) |
| TBU | This Binary Universe (band) |
| TBU | Nuku Alofa/Tongatapu, Tonga - International (Airport Code) |
| TBU | Tone-Bearing Unit (linguistics) |
| TBU | Telephone Balance Unit (broadcast radio industry) |
| TBU | Time Base Unit (microcontroller) |
| TBU | The Brand Union (Singapore) |
| TBU | Teabaggers United (gaming clan) |
| TBU | Technical Business Unit |
| TBU | Telemetry Buffer Unit |
| TBU | The Big Unit (Australian Football League Player) |
| TBU | Test Before Using |
| TBU | Tirana Business University (Tirana, Albania) |
| TBU | Technisch Bureau Uittenbogaart (Netherlands) |
| TBU | Telephone Balancing Unit |
| TBU | Terminal Buffer Unit |
| TBU | Throttle Body Unit (automotive fuel injection system) |
| TBU | Test By User |
| TBU | Thorium-Bred Uranium (nuclear fuel) |