| Acronym | Definition |
|---|
| UPF | Universitat Pompeu Fabra (Barcelona, Spain) |
| UPF | Ultraviolet Protection Factor |
| UPF | Universidade de Passo Fundo (Portuguese: University of Passo Fundo; Brazil) |
| UPF | Unified Power Format (IEEE standard) |
| UPF | University Press of Florida |
| UPF | Universal Peace Federation (formerly Interreligious and International Federation for World Peace) |
| UPF | Uncharacterized Protein Family |
| UPF | Union Internationale de la Presse Francophone (French: International Francophone Press Union; France; est. 1950) |
| UPF | Unity Productions Foundation |
| UPF | United People's Front (Nepal) |
| UPF | Upcountry People's Front (Sri Lanka) |
| UPF | Universal Preservation Format |
| UPF | Unity Power Factor (electrical engineering) |
| UPF | Unidade de Protecção da Força (Portuguese: Force Protection Unit) |
| UPF | Underperform (finance) |
| UPF | Urban Parks Forum (est. 1999) |
| UPF | United Plastic Fabricating, Inc. (North Andover, MA) |
| UPF | University Police Force (University of the Philippines) |
| UPF | United Peace Federation |
| UPF | Un-Plug Fest (Bluetooth) |