| Acronym | Definition |
|---|
| USM | USB (Universal Serial Bus) Storage Media |
| USM | Ultrasonic Motor |
| USM | University of Southern Mississippi |
| USM | University of Southern Maine (Portland and Gorham, Maine, USA) |
| USM | Universiti Sains Malaysia |
| USM | University System of Maryland |
| USM | Universal Storage Module (standard) |
| USM | Union Square Music (UK) |
| USM | User-based Security Model (Simple Network Management Protocol) |
| USM | Universal Subscription Mechanism |
| USM | Unstoppable Sex Machine (band) |
| USM | Ultimate Spider-Man (comic) |
| USM | User Based Security Model |
| USM | Unsharp Masking |
| USM | Usb Memory Stick |
| USM | United States Military |
| USM | Koh Samui, Thailand (Airport Code) |
| USM | Union Syndicale des Magistrats (French: Trade Union of Judges) |
| USM | Carter the Unstoppable Sex Machine (band) |
| USM | Unsharp Masking (image/edge sharpening technique) |
| USM | University of Saint Mary (Leavenworth, Kansas) |
| USM | Universidad Santa María (Valparaiso, Chile) |
| USM | Universidad Santa María (Caracas, Venezuela) |
| USM | University of Southern Mindanao |
| USM | United States Marshal |
| USM | Unlisted Securities Market |
| USM | User State Migration (software; also seen as USMT) |
| USM | User Security Model |
| USM | Ultimate Soccer Manager (soccer game) |
| USM | United States Marines |
| USM | Universal Service Market |
| USM | United States Mail |
| USM | Ultrasonic Meter |
| USM | Union Sportive Monastirienne (Tunisia) |
| USM | United Super Market |
| USM | Under Secretary for Management |
| USM | Unofficial Student Manual (social site) |
| USM | United Shoe Machinery Corporation |
| USM | Underwater-To-Surface Missile |
| USM | United States Militia (Battlefield 1942 clan) |
| USM | Unified Security Manager (policy) |
| USM | User Session Manager |
| USM | Unit Security Manager |
| USM | User Schedule Message (NASA) |
| USM | Underlying Subject Matter (UK tax regulations) |
| USM | Ultimate Street Machines, Inc (Hanover, MD) |
| USM | Unit Sergeant Major |
| USM | User Security Manual |
| USM | Uniform Staffing Methodology |
| USM | Un-Scheduled Maintenance |
| USM | Uniform Sampling Method |
| USM | Universal Synthesizer Module |
| USM | Unified Spectrum Management |