| Acronym | Definition |
|---|
| TLB | Type Library (file extension) |
| TLB | Translation Lookaside Buffer |
| TLB | Tractor-Loader-Backhoe |
| TLB | Tapeless Backup |
| TLB | Tool Bar |
| TLB | Translation Bridging |
| TLB | Text Library |
| TLB | Type Library |
| TLB | The Living Bible |
| TLB | True Launch Bar (software) |
| TLB | Transmit Load Balancing (Hp) |
| TLB | Tournament Leader Board |
| TLB | Taro Leaf Blight (plant disease) |
| TLB | The Lost Boys (movie) |
| TLB | Top Level Budget |
| TLB | Term Loan B |
| TLB | Transport Licensing Board |
| TLB | Tie Line (Class) B |
| TLB | Transport Load Builder |
| TLB | Toilette à Litière Biomaîtrisée (French: Biocontrolled Toilet Litter) |
| TLB | Table Lookaside Buffer |
| TLB | True Last Boss (video gaming) |
| TLB | Time-Life Books |
| TLB | The Lazy Bastards (gaming clan) |
| TLB | Typical Liberal Behavior |
| TLB | The Lascivious Biddies (band) |
| TLB | Tastes Like Burning (band) |
| TLB | Trade Law Branch |
| TLB | Technical Log Book (aviation) |
| TLB | Trailer Launched Bridge |
| TLB | Tout Le Bois (French) |
| TLB | Test Loop Back |
| TLB | Thread Local Buffer |
| TLB | Tyler Lenius Band |
| TLB | Thieving Lying Bastards |
| TLB | Tie Line Biased |
| TLB | The Learning Box LLC |