| Acronym | Definition |
|---|
| VDI | Virtual Desk Infrastructure (computing model) |
| VDI | Virtual Desktop Infrastructure |
| VDI | Virtual Disk Image |
| VDI | Valsts Darba Inspekcijas (Latvian: State Labour Inspection) |
| VDI | Virtual Device Interface |
| VDI | Video Data Input |
| VDI | Video Disk Interactive |
| VDI | Variable Intake Diesel Direct Injection |
| VDI | Video Display Input |
| VDI | Vector Display Indicator |
| VDI | Video Data Interface |
| VDI | Virtual Development Interface |
| VDI | Vendeur à Domicile Indépendant (French: Independent Home Vendor; vendor status; France) |
| VDI | Voix, Données, Images (French: Voice, Data, Image; building communication channels) |
| VDI | Verein Deutsche Ingenieure (Society of German Engineers) |
| VDI | Vested Development, Inc. (Burlington, MA) |
| VDI | Video Display Interface |
| VDI | Vantan Design Institute (Japan) |
| VDI | Vehicle Dependability Index (JD Powers) |
| VDI | Video Device Interface |
| VDI | Visual Defence, Inc. (Canada) |
| VDI | Vista Drive Icon (software) |
| VDI | Voluntary Disability Insurance |
| VDI | V Differential Input |
| VDI | Vending Data Interchange (wireless telemetry) |
| VDI | Vertical Display Indicator |
| VDI | Verbal Dispatch Instruction |
| VDI | Vesicular Stomatitis Virus Defective Interfering Particle Repressor |
| VDI | Verification, Design and Implementation |
| VDI | Voice Data Integrator |
| VDI | Verify Dispatch Information (Dell) |