| Acronym | Definition |
|---|
| APSC | Arkansas Public Service Commission |
| APSC | Alabama Public Service Commission |
| APSC | Alyeska Pipeline Service Company |
| APSC | African People's Solidarity Committee (Oakland, CA) |
| APSC | Asian Pacific Student Coalition (University of Pennsylvania) |
| APSC | Average Percentage Statement Coverage (algorithms) |
| APSC | Asamblea para la Promoción de la Sociedad Civil (Spanish: Assembly for the Promotion of Civil Society; Cuba) |
| APSC | Asia Pacific Support Collective (Darwin, Australia) |
| APSC | Airline Passenger Service Commitment (voluntary commitment to deliver defined standards of service) |
| APSC | Aquatic Performance Swim Club Singapore |
| APSC | Alert Pipe and Supply Company (Bay City, Michigan) |
| APSC | Arizona Public Service Commission |