| Acronym | Definition |
|---|
| YSL | Yves Saint Laurent |
| YSL | Youth Soccer League (various locations) |
| YSL | Yolk Syncytial Layer |
| YSL | Youth Ski League |
| YSL | Yugoslavian Sign Language (SIL code) |
| YSL | St Leonard, New Brunswick, Canada - St Leonard Apt (Airport Code) |
| YSL | Yarrow Shipbuilders Ltd. (UK) |
| YSL | Young Successful Living |
| YSL | Your Second Life |
| YSL | Youth Service Learning |
| YSL | Yavapai Soccer League (Prescott Valley, AZ) |
| YSL | Yamashita-Shinnihon Steamship Co., Ltd (Japan) |
| YSL | Yale Student Loan |
| YSL | Yale Student Loans |
| YSL | Youth Service Leadership |
| YSL | Yolo Shortline Railroad |
| YSL | Youth Service League |
| YSL | Yayasan Simeuleu Lestari |
| YSL | Yap State Law (Micronesia) |
| YSL | Yautja Shadow Legions (gaming) |
| YSL | Yellowstripe-Like |
| YSL | Yale Student Laundry |
| YSL | Youth Swim Lessons (YMCA swim instructor course) |
| YSL | Yuba Sutter Life (California) |
| YSL | Youth Servant Leader |
| YSL | YMCA Swim League |
| YSL | Yorke Structures Ltd |
| YSL | Yayasan Sahabat Lingkungan (Jakarta, Indonesia) |
| YSL | Your School and the Law |
| YSL | Young Scout Leader |
| YSL | Your Sweden Luxury (clothing brand) |