| Acronym | Definition |
|---|
| YOLO | You Only Live Once |
| YOLO | You Only Love Once (album) |
| YOLO | You Obviously Love Oreos |
| YOLO | You Obviously Love One Direction |
| YOLO | You Only Lifted Once |
| YOLO | You Only Live Online |
| YOLO | Youth Obeying Lucifer's Orders |
| YOLO | You Only Laugh Once |
| YOLO | You Oughta Look Out |
| YOLO | You Only Love Oreos |
| YOLO | You Obviously Lack Originality |
| YOLO | You Only Leave Once |
| YOLO | You Obviously Love Octavia |
| YOLO | You Only Love Owls |
| YOLO | You Only Like Oranges |
| YOLO | You Only Like Oreos |
| YOLO | You're Only Loved Online |
| YOLO | You Only Log On |
| YOLO | Yell Out Loud Obnoxiously |
| YOLO | You Obviously Like Oatmeal (gaming) |
| YOLO | Your Only Lesbian Online |
| YOLO | You Oughta Love Orangutans |