| Acronym | Definition |
|---|
| WPI | Worcester Polytechnic Institute (Worcester, MA) |
| WPI | Whey Protein Isolate |
| WPI | Watson Pharmaceuticals, Inc. |
| WPI | Wraps Per Inch (weaving) |
| WPI | Wholesale Price Index |
| WPI | World Precision Instruments (various locations) |
| WPI | World Policy Institute |
| WPI | Web Printing Interface |
| WPI | Worldwide Partners, Inc. (Denver, CO) |
| WPI | Whole Person Impairment |
| WPI | Work Process Improvement |
| WPI | Weeks Post Injury (healthcare) |
| WPI | Water Poverty Index |
| WPI | World Patent Index |
| WPI | World Press Institute |
| WPI | World Peace International |
| WPI | Women's Philanthropy Institute |
| WPI | Willem Pompe Instituut (Dutch school) |
| WPI | Waste Policy Institute |
| WPI | Weider Publications, Inc. (Delaware) |
| WPI | Weather Protected Type I (electric motors) |
| WPI | When Buttersnaps Appear Peaches No Longer Interest Me |
| WPI | Wealth Preservation Institute (St. Joseph, MI) |
| WPI | Wisconsin Pain Initiative |
| WPI | Women and Politics Institute (American University) |
| WPI | Worker Process Isolation (Microsoft) |
| WPI | West Point Inn (Mill Valley, CA) |
| WPI | Whalley Precision, Inc. |
| WPI | Winter Properties, Inc. |
| WPI | Work Product Inspection |
| WPI | Weight Parameter Initialization |
| WPI | War Paint Illustrated (print magazine) |