| Acronym | Definition |
|---|
| WPO | Web Performance Optimization |
| WPO | Women Presidents' Organization (New York, NY) |
| WPO | World Packaging Organization |
| WPO | Word Processing Operator |
| WPO | Word Perfect Office |
| WPO | World Public Opinion (Washington, DC) |
| WPO | Water Protection Ordinance (various locations) |
| WPO | Workplace Organization (business philosophy) |
| WPO | Wildlife Protection Office (various locations) |
| WPO | World Powerlifting Organization |
| WPO | Worldwide Pharmaceutical Operations (Pfizer) |
| WPO | Writers Project Organizer (software) |
| WPO | Women's Progressive Organization |
| WPO | Werkplek Onderzoek (Netherlands) |
| WPO | Wiener Philharmoniker Orchestra (Austria) |