| Acronym | Definition |
|---|
| VME | Virtual Machine Environment (an operating system of ICL mainframes) |
| VME | Versa Module Eurocard |
| VME | Virtual Memory Environment |
| VME | Virtual Machine Environment |
| VME | Virtual Mode Extension |
| VME | Virtual Home Environment |
| VME | Vietnam Museum of Ethnology (Hanoi, Vietnam) |
| VME | Versa Module Eurocard (IEEE 1014) |
| VME | Virtual Matrix Encryption (Meganet) |
| VME | Vintage Motorcycle Enthusiasts |
| VME | Vulnerable Marine Ecosystem |
| VME | Virtual Medical Exhibition (electronic commerce) |
| VME | Virtual Memory Extension |
| VME | Visual Modelling Environment |
| VME | Virtual Memory Extended |
| VME | Virtual-8086 Mode Enhancement (computing) |
| VME | Verso Modulo Europa |
| VME | Verotoxic Meningoencephalitis |
| VME | Voluntary Observing Ship |
| VME | Valeur Limite de Moyenne d'Exposition Professionnelle (French: time-weighted average) |