| Acronym | Definition |
|---|
| BLISS | Bass Level Isolating Soft Silicon (music) |
| BLISS | Blind Source Separation |
| BLISS | Bilkent Library Information Services System |
| BLISS | Bagong Lipunan Improvement of Sites and Services (Philippines) |
| BLISS | Bio-Inspired Learning and Intelligent Systems for Security (symposium) |
| BLISS | Broadband Local Integrated Services Solution (Cisco) |
| BLISS | Behavioral Lightweight Intelligence for Stressed Systems (Ziften Technologies) |
| BLISS | Body-based pleasure, Laughter, Involvement, Satisfaction and Sex |
| BLISS | Basic Language for Implementing System Software (DEC PDP-10) |
| BLISS | Beamline Instrument Software Support |
| BLISS | Balloon-Borne Laser In-Situ Sensor |
| BLISS | Boundary Layer Infrared Suppression System |
| BLISS | Base Level Integrated Support System |
| BLISS | Blend, Low Silhouette, Irregular Shape, Small, Secluded Location (military shelter site selection) |