COTC
| Acronym | Definition |
|---|---|
| COTC | Clan of the Cats (webcomic) |
| COTC | Cream of the Crop (Chronsky music) |
| COTC | Central Ohio Technical College |
| COTC | Church Of The Creator (hate group) |
| COTC | Corn on the Cob |
| COTC | Canadian Officer Training Corps (Canada) |
| COTC | Commanding Officer, Training Contingent |
| COTC | Channel-Optimized Transform Code |