| Acronym | Definition |
|---|
| COTD | Color of the Day |
| COTD | Call of the Dead (gaming) |
| COTD | Card of the Day (gaming) |
| COTD | Chart of the Day |
| COTD | Climb out of the Darkness (Postpartum Support International) |
| COTD | Cross of the Dutchman (gaming) |
| COTD | Clash of the Dragons (card game) |
| COTD | Catch Of The Day |
| COTD | Creatures of the Deep (N-Gage game) |
| COTD | Coaltar of the Deepers (Japan band) |
| COTD | Comment of the Day |
| COTD | City of the Dead |
| COTD | Children of the Damned |
| COTD | Cat of the Day |
| COTD | City of the Damned |
| COTD | Circle of True Doom |
| COTD | Complete on Time Delivery (shipping) |
| COTD | Customer of the Day |
| COTD | Cult of the Dolphin |
| COTD | Cache of the Day (geocaching) |
| COTD | Cardiac Output Obtained by Thermodilution |
| COTD | Call Off the Dogs |
| COTD | Clan of the Dragon |
| COTD | Cotangent of x in Degrees |