COTU
| Acronym | Definition |
|---|---|
| COTU | Creator of the Universe |
| COTU | Central Organisation of Trade Unions (Kenya) |
| COTU | Center of The Universe |
| COTU | Companions of True Unity (Islamic band) |
| COTU | Cities of the Underworld (television program) |
| COTU | Crude Oil Topping Unit (oil processing; Alaska) |
| COTU | Corner of the Universe |