| Acronym | Definition |
|---|
| COTW | Clip of The Week |
| COTW | Coalition of the Willing |
| COTW | Cat on the Wall |
| COTW | Case of the Week |
| COTW | Concept of the Week (various organizations) |
| COTW | Committee of the Whole (legislation) |
| COTW | Creation of the Week |
| COTW | Church of the Week (various locations) |
| COTW | Call of the Wild |
| COTW | Covenant of the Witches |
| COTW | Cringe of the Week |
| COTW | Catch of the Week |
| COTW | Collaboration of the Week (Wikimedia Foundation) |
| COTW | Composer of the Week (British Broadcasting Corporation Radio 3 Program) |
| COTW | Castle of the Winds (role playing game) |
| COTW | Cars on the Web (remarketing company) |
| COTW | Citizens of the World |
| COTW | Club of the Waves (surf website) |
| COTW | Cow of the Wild (online animated series) |
| COTW | Courts of the World (basketball website) |
| COTW | Center of the World |
| COTW | Colors of the Wind (Disney song) |
| COTW | Cousins of the Wize (band) |
| COTW | Crush of the Week (also seen as COW) |
| COTW | Call of The Warlords (game) |
| COTW | Contest of the Week |
| COTW | Cheerleader of the Week |
| COTW | Conflict Other Than War |
| COTW | Creature of the Week (website) |
| COTW | Clans of the Waterfalls (role-playing) |
| COTW | Church on the Web |
| COTW | Camp of the Woods Ministries, Inc (Chattanooga, TN) |
| COTW | Chuck on the Web (personal website) |
| COTW | Curse of the Wookie (Star Wars) |
| COTW | Courage of the Wolves (game) |