BUFF
| Acronym | Definition |
|---|---|
| BUFF | Buffalo |
| BUFF | Buffer |
| BUFF | Boston Underground Film Festival (Boston, MA) |
| BUFF | Buffalo National River (US National Park Service) |
| BUFF | Big Ugly Fat Fellow (polite form) |
| BUFF | CC-115 Buffalo (Canadian transport and rescue aircraft) |
| BUFF | Big Ugly Flying Fellow (USAF B-52 Bomber, polite form) |