| Acronym | Definition |
|---|
| BFF | Best Friends Forever (chat) |
| BFF | Blueprint for the Future (National Aboriginal Achievement Foundation; Canada) |
| BFF | Best Female Friend |
| BFF | Best Facebook Friend |
| BFF | Best Friends Funeral (senior slang) |
| BFF | Big Fat Friend |
| BFF | Bangladesh Football Federation (est. 1972; governing body) |
| BFF | Bicycle Film Festival (various locations) |
| BFF | Best Fan Forever |
| BFF | Budget Friendly Food |
| BFF | Browse for Folder |
| BFF | Backup File Format |
| BFF | Best Foot Forward |
| BFF | Bottom Field First (video field order) |
| BFF | Ben Folds Five (band) |
| BFF | Basic Fire Fighting (course) |
| BFF | British Forces Foundation (UK) |
| BFF | Best Friend Farted |
| BFF | Black Footed Ferret |
| BFF | Born Free Foundation |
| BFF | Badminton for Fun |
| BFF | Binary File Format |
| BFF | Boston Film Festival |
| BFF | Body Fixed Frame (physics) |
| BFF | Bioexpression and Fermentation Facility (University of Georgia) |
| BFF | Bradford Film Festival (UK) |
| BFF | Breckenridge Festival of Film (Breckenridge, CO) |
| BFF | Bring Friend and Family |
| BFF | Beyond Final Fantasy (gaming) |
| BFF | Bozeman Film Festival (Montana) |
| BFF | Brattle Film Foundation (Cambridge, MA) |
| BFF | Scottsbluff, NE, USA - William B Heiling Field (Airport Code) |
| BFF | Biotech Finance Forum |
| BFF | Blanche Fischer Foundation |
| BFF | Bags Fly Free (Southwest Airlines) |
| BFF | Bank Failure Friday |
| BFF | Barely Freaking Friends |
| BFF | Boyfriend Forever |
| BFF | Best Frenemies Forever |
| BFF | British Farming Forum (UK) |
| BFF | Biblical Foundations for Freedom |
| BFF | Best Foam Fabricators, Inc. (Chicago, IL) |
| BFF | Best Freakin Friend |
| BFF | Below Finished Floor (architectural, mechanical drawings) |
| BFF | Brake Fluid Flush (automotive) |
| BFF | Buffered Flip-Flop |
| BFF | Benchmark Format Form |
| BFF | Budget Formulation & Forecasting |
| BFF | Black Friend Forever |
| BFF | Belgische Federatie van Fotografen (Dutch: Belgian Federation of Photographers; Belgium) |
| BFF | BruksprovsFörarFörenigen |
| BFF | Bit-Map-Based First Fit |
| BFF | Bonsoir François Feldman (band) |
| BFF | Books Found Fast (book retailer; UK) |
| BFF | Bush Fire Fighter (Australia) |